【基本信息】
姓名：牛庆芬
职称：副教授/硕士研究生导师
单位：js6666金沙登录入口-官方入口化学与制药工程学院，山东省分子工程重点实验室522
地址：济南市长清区大学路3501号
【研究方向】
1、有机合成化学及有机合成新方法
2、高效有机光伏材料的设计、合成及性能研究
3、新型高性能分子荧光探针的构建，包括可见光、近红外和双光子荧光探针的设计合成及应用研究
4、生物医学成像研究，包括活细胞、活组织及动物活体荧光成像研究
【教育工作背景】
2014年，js6666金沙登录入口-官方入口，副教授
2013年，山东体育大学，有机化学，博士
2008年，山东师范大学，化学，学士
【教研科研项目】
1. 校级研究生教育优质课程建设项目《合成化学》，2018，主持
2. 校级教研项目《化学化工“大类招生、分类培养”模式的实践与探索》，2015，主持
3. 山东省自然科学基金-- A-π-D-π-A型有机光伏给体材料的设计、合成及其性能研究，2017，主持
4. 山东省教改项目，2019，主持
【代表性学术论文】（发表SCI论文55余篇，被引频次1021次，H指数为22）
2019年
1. Zongrang Guo, Tingting Hu, Xingjian Wang, Tao Sun, Tianduo Li,* Qingfen Niu*, Highly sensitive and selective fluorescent sensor for visual detection of Cu2+ in water and food samples based on oligothiophene derivative, Journal of Photochemistry and Photobiology A: Chemistry 37 (2019) 50-58.
2. Yang Li, Qingfen Niu*, Tao Wei, Tianduo Li*, Novel thiophene-based colorimetric and fluorescent turn-on sensor for highly sensitive and selective simultaneous detection of Al3+ and Zn2+ in water and food samples and its application in bioimaging, Analytica Chimica Acta 1049 (2019) 196-212.
3. Zongrang Guo, Tingting Hu, Tao Sun, Tianduo Li*, Hong Chi, Qingfen Niu*, A colorimetric and fluorometric oligothiophene-indenedione-based sensor for rapid and highly sensitive detection of cyanide in real samples and bioimaging in living cells, Dyes and Pigments 163 (2019) 667–674.
4. Zongrang Guo, Qingfen Niu*, Tianduo Li, Tao Sun, Hong Chi, A fast, highly selective and sensitive colorimetric and fluorescent sensor for Cu2+ and its application in real water and food samples, Spectrochimica Acta Part A：Molecular and biomolecular spectroscopy 213 (2019) 97–103.
5. Zongrang Guo, Qingfen Niu*, Qingxin Yang, Tianduo Li, Hong Chi, A highly selective and sensitive dual-mode sensor for colorimetric and turn-on fluorescent detection of cyanidein water, agro-products and living cells, Analytica Chimica Acta1065 (2019) 113-123.
6. Junjie Wang, Tao Wei, Feng Ma, Tianduo Li*, Qingfen Niu*, A novel fluorescent and colorimetric dual-channel sensor for the fast, reversible and simultaneous detection of Fe3+ and Cu2+ based on terthiophene derivative with high sensitivity and selectivity, Journal of Photochemistry and Photobiology A: Chemistry 383 (2019) 111982.
7. Zhenyu Zuo*, Xiaomei Song, Dongyan Guo, Zongrang Guo, Qingfen Niu*, A dual responsive colorimetric/fluorescent turn-on sensor for highly selective, sensitive and fast detection of Fe3+ ions and its applications, Journal of Photochemistry and Photobiology A: Chemistry 382 (2019) 111876.
8. Zongrang Guo, Qingfen Niu*, Tianduo Li, Enhua Wang, Highly chemoselective colorimetric/fluorometric dual-channel sensor with fast response and good reversibility for the selective and sensitive detection of Cu2+, Tetrahedron 75 (2019) 3982–3992.
9. Junjie Wang, Qingfen Niu*, Tingting Hu, Tianduo Li, Tao Wei, A new phenothiazine-based sensor for highly selective, ultrafast, ratiometric fluorescence and colorimetric sensing of Hg2+: Applications to bioimaging in living cells and test strips, Journal of Photochemistry and Photobiology A: Chemistry 384 (2019) 112036.
10. Chunpeng Li, Qingfen Niu*, Shanshan Zhang, Tianduo Li, Qingxin Yang, Synthesis, photophysical and electrochemical properties of a new star-shaped molecule with a 1,3,5-triethynylbenzene core and diketopyrrolopyrrole arms, RSC Advances 9 (2019) 28357–28363.
11. Pengcheng Yin, Qingfen Niu*, Qingxin Yang, Linxin Lan, Tianduo Li, A new “naked-eye” colorimetric and ratiometric fluorescent sensor for imaging Hg2+ in living cells, Tetrahedron, 75 (2019) 130687.
12. Pengcheng Yin, Qingfen Niu,* Tao Wei, Tianduo Li,Yang Li, Qingxin Yang, A new thiophene-based dual functional chemosensor for ultrasensitive colorimetric detection of Cu2+ in aqueous solution and highly selective fluorimetric detection of Al3+ in living cells, Journal of Photochemistry and Photobiology A: Chemistry 2019, in press.
2018年
7. Linxin Lan, Qingfen Niu*, Tianduo Li, A highly selective colorimetric and ratiometric fluorescent probe for instantaneous sensing of Hg2+ in water, soil and seafood and its application on test strips, Analytica Chimica Acta 1023 (2018) 105-114.
8. Linxin Lan, Tianduo Li, Tao Wei, He Pang, Tao Sun, Enhua Wang, Haixia Liu, Qingfen Niu*, Oligothiophene-based colorimetric and ratiometric fluorescence dual-channel cyanide chemosensor: Sensing ability, TD-DFT calculations and its application as an efficient solid state sensor, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 193 (2018) 289–296.
9. Shanshan Zhang, Tao Sun, Dejun Xiao, Fang Yuan, Tianduo Li, Enhua Wang, Haixia Liu, Qingfen Niu*, A dual-responsive colorimetric and fluorescent chemosensor based on diketopyrrolopyrrole derivative for naked-eye detection of Fe3+ and its practical application, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 189 (2018) 594–600.
10. Tao Sun, Qingfen Niu*, Tianduo Li, Zongrang Guo, Haixia Liu, A simple, reversible, colorimetric and water-soluble fluorescent chemosensor for the naked-eye detection of Cu2+ in ~ 100% aqueous media and application to real samples, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 188 (2018) 411–417.
2017年
4. Shanshan Zhang, Qingfen Niu*, Tao Sun, Yang Li, Tianduo Li, Haixia Liu, The synthesis and properties of linear A–π–D–π–A type organic small molecule containing diketopyrrolopyrrole terminal units, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 183 (2017) 172–176.
5. Shanshan Zhang, Xingxing Wu, Qingfen Niu*, Zongrang Guo, Tianduo Li, Haixia Liu, Highly Selective and Sensitive Colorimetric and Fluorescent Chemosensor for Rapid Detection of Ag+, Cu2+ and Hg2+ Based on a Simple Schiff Base, Journal of Fluorescence 27 (2017) 729–737.
6. Tao Sun, Qingfen Niu*, Zongrang Guo, Tianduo Li, A simple highly sensitive and selective turn-on fluorescent chemosensor for the recognition of Pb2+, Tetrahedron Letters 58 (2017) 252-256.
7. Shanshan Zhang, Tao Sun, Zhen Xu, Tianduo Li, Yang Li, Qingfen Niu*, Haixia Liu, Novel biphenylene-diketopyrrolopyrrole-based A-π-D-π-A molecule: Synthesis, optical, electrochemical and electronical properties, Tetrahedron Letters 58 (2017) 2779-2783.
2. Qingfen Niu*, Xingxing Wu, Tianduo Li, Yuezhi Cui, Shanshan Zhang, Xiaoyan Li, Highly selective, sensitive and fast-responsive fluorescent sensor for Hg2+, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 163 (2016) 45–48.
3. Qingfen Niu*, Xingxing Wu, Tianduo Li, Yuezhi Cui, Shanshan Zhang, Qiuchen Su, A Phenylamine-Oligothiophene-Based Fluorescent Chemosensor for Selective Detection of Hg(II), Journal of Fluorescence 26 (2016) 1053–1058.
5. Xingxing Wu, Qingfen Niu*, Tianduo Li, Yuezhi Cui, Shanshan Zhang, A highly sensitive, selective and turn-off fluorescent sensor based on phenylamine-oligothiophene derivative for rapid detection of Hg2+, Journal of Luminescence 175 (2016) 182–186.
7. Qingfen Niu*, Xingxing Wu, Shanshan Zhang, Tianduo Li, Yuezhi Cui, Xiaoyan Li, A highly selective and sensitive fluorescent sensor for the rapid detection of Hg2+ based on phenylamine-oligothiophene derivative, Spectrochimica Acta Part A Molecular and biomolecular spectroscopy 153 (2016) 143-146.
8. Xingxing Wu, Shanshan Zhang, Qingfen Niu*, Tianduo Li*, A novel urea-derived fluorescent sensor for highly selective and sensitive detection of Fe3+, Tetrahedron Letters 57 (2016) 3407-3411.
9. Qiuchen Su, Qingfen Niu*, Tao Sun, Tianduo Li, A simple fluorescence turn-on chemosensor based on Schiff-base for Hg2+-selective detection, Tetrahedron Letters 57 (2016) 4297-4301.
1. Shanshan Zhang, Qingfen Niu*, Xingxing Wu, Tianduo Li, Yuezhi Cui, Xiaoyan Li, A Fast-Responsive Fluorescent Sensor for Hg2+ with High Selectivity and Sensitivity in Aqueous Media, Journal of Fluorescence 25 (2015) 1543–1548.
2. Qingfen Niu, Xiaohan Zhang, Shumiao Zhang, Xiaoyan Li, Hongjian Sun*, Activation of vinylic carbon-chlorine bond by nickel complexes supported with phosphine ligands, Inorganica Chimica Acta 426 (2015) 165-170.
2014-2012年
1. Qingfen Niu, Hongjian Sun, Lin Wang, Qingping Hu*, Xiaoyan Li*, Reactivity of mer-hydrido(2-mercaptobenzoyl)-tris(trimethylphosphine)cobalt( III ) complex, Dalton Trans. 43 (2014) 4059−4066.
2.Qingfen Niu, Hongjian Sun, Xiaoyan Li*, Synthesis, photophysical and thin-film self-assembly properties of novel fluorescent molecules with carbon–carbon triple bonds, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 133 (2014) 229–240.
3. Qingfen Niu, Yunqiang Lu, Hongjian Sun, Xiaoyan Li*, Xutang Tao*, Novel phenyl-oligothiophene derivatives containing acetylenic spacers for thin film materials: Synthesis, photophysical and morphology properties, Dyes and Pigments 97 (2013) 184−197.
4. Qingfen Niu, Hongjian Sun, Xiaoyan Li*, H.-F. Klein, Ulrich Flörke, Synthesis and Catalytic Application in Hydrosilylation of the Complex mer-Hydrido(2-mercaptobenzoyl)tris-(trimethylphosphine)cobalt(III), Organometallics 32 (2013) 5235−5238.
5. Qingfen Niu, Yunqiang Lu, Hongjian Sun, Xiaoyan Li*, Novel planar and star-shaped molecules: Synthesis, electrochemical and photophysical properties, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 107 (2013) 377–385.
6. Qingfen Niu, Xiaofeng Xu, Hongjian Sun, Xiaoyan Li*, Synthesis of 2-Mercaptobenzaldehyde, 2-Mercaptocyclohex-1-enecarboxaldehydes and 3-Mercaptoacrylaldehydes, Chin. J. Chem. 30 (2012) 2495–2500.
【学术兼职】
中国化学会会员；山东省化工协会会员；担任《Nanoscale》、《Current Organic Chemistry》、《Journal of Hazardous Materials》、《Sensors and Actuators B: Chemical》、《Analytical Chemistry》、《Analytica Chimica Acta》、《Analyst》、《Analytical Methods》、《Talanta》、《New Journal of Chemistry》、《Spectrochimica Acta Part A》、《Polymer Chemistry》、《RSC Advances》、《ACS Omega》、《ACS Sustainable Chemistry and Engineering》、《ACS Applied Materials & Interfaces》、《Dalton Transactions》、《Applied Organometallic Chemistry》、《Journal of Photochemistry and Photobiology A: Chemistry》、《Sensors》、《Food Chemistry》、《Inorganica Chimica Acta》、《Chemical Research in Toxicology》、《Small》、《Journal of the Chinese Chemical Society》等国际知名期刊的审稿专家。
【奖励与荣誉】
1. 山东省研究生优秀创新成果三等奖，共同指导教师，2019
2. 山东省优秀硕士学位论文2篇，共同指导教师，2019
3. 国家级研究生奖学金，共同指导教师，2019
4. 山东省省级教学成果二等奖，2018
5. 山东省研究生优秀科技创新成果三等奖，共同指导教师, 2018
6. js6666金沙登录入口-官方入口研究生优秀硕士学位论文，共同指导教师，2018
7. js6666金沙登录入口-官方入口研究生优秀创新成果二等奖，共同指导教师, 2018
8. js6666金沙登录入口-官方入口研究生优秀创新成果一等奖，共同指导教师, 2017
9. js6666金沙登录入口-官方入口研究生优秀创新成果三等奖，共同指导教师, 2017
10. js6666金沙登录入口-官方入口大学生创新创业训练计划，指导教师, 2018
11. 国家级大学生创新创业训练计划，指导教师, 2019
12. 国家级大学生创新创业训练计划，指导教师, 2017
13. 国家级大学生创新创业训练计划，指导教师，2015
【教学经历】
1. 本科生课程：学术班《无机化学》、《无机化学实验》、《化学专业综合实验》及《毕业论文》
2. 硕士生课程：《现代有机合成化学》、《合成化学》
【研究生培养】
目前，培养研究生10名，已毕业研究生5名，其中1人考入中国科技大学攻读博士学位；1人进入山东中医药大学在编教师；1人从事高中教师职业；3人次获国家级研究生奖学金，多人获校级奖学金。
